Validation of a virtual source model of medical linac for Monte Carlo dose calculation using multi-threaded Geant4.
Identifieur interne : 000447 ( Main/Exploration ); précédent : 000446; suivant : 000448Validation of a virtual source model of medical linac for Monte Carlo dose calculation using multi-threaded Geant4.
Auteurs : Zakaria Aboulbanine [Maroc] ; Naïma El KhayatiSource :
- Physics in medicine and biology [ 1361-6560 ] ; 2018.
Descripteurs français
- KwdFr :
- Accélérateurs de particules (MeSH), Algorithmes (MeSH), Bases de données factuelles (MeSH), Dosimétrie en radiothérapie (MeSH), Humains (MeSH), Langages de programmation (MeSH), Logiciel (MeSH), Loi normale (MeSH), Méthode de Monte Carlo (MeSH), Photons (MeSH), Planification de radiothérapie assistée par ordinateur (méthodes), Reproductibilité des résultats (MeSH), Simulation numérique (MeSH).
- MESH :
- méthodes : Planification de radiothérapie assistée par ordinateur.
- Accélérateurs de particules, Algorithmes, Bases de données factuelles, Dosimétrie en radiothérapie, Humains, Langages de programmation, Logiciel, Loi normale, Méthode de Monte Carlo, Photons, Reproductibilité des résultats, Simulation numérique.
English descriptors
- KwdEn :
- Algorithms (MeSH), Computer Simulation (MeSH), Databases, Factual (MeSH), Humans (MeSH), Monte Carlo Method (MeSH), Normal Distribution (MeSH), Particle Accelerators (MeSH), Photons (MeSH), Programming Languages (MeSH), Radiotherapy Dosage (MeSH), Radiotherapy Planning, Computer-Assisted (methods), Reproducibility of Results (MeSH), Software (MeSH).
- MESH :
Abstract
The use of phase space in medical linear accelerator Monte Carlo (MC) simulations significantly improves the execution time and leads to results comparable to those obtained from full calculations. The classical representation of phase space stores directly the information of millions of particles, producing bulky files. This paper presents a virtual source model (VSM) based on a reconstruction algorithm, taking as input a compressed file of roughly 800 kb derived from phase space data freely available in the International Atomic Energy Agency (IAEA) database. This VSM includes two main components; primary and scattered particle sources, with a specific reconstruction method developed for each. Energy spectra and other relevant variables were extracted from IAEA phase space and stored in the input description data file for both sources. The VSM was validated for three photon beams: Elekta Precise 6 MV/10 MV and a Varian TrueBeam 6 MV. Extensive calculations in water and comparisons between dose distributions of the VSM and IAEA phase space were performed to estimate the VSM precision. The Geant4 MC toolkit in multi-threaded mode (Geant4-[mt]) was used for fast dose calculations and optimized memory use. Four field configurations were chosen for dose calculation validation to test field size and symmetry effects, [Formula: see text] [Formula: see text], [Formula: see text] [Formula: see text], and [Formula: see text] [Formula: see text] for squared fields, and [Formula: see text] [Formula: see text] for an asymmetric rectangular field. Good agreement in terms of [Formula: see text] formalism, for 3%/3 mm and 2%/3 mm criteria, for each evaluated radiation field and photon beam was obtained within a computation time of 60 h on a single WorkStation for a 3 mm voxel matrix. Analyzing the VSM's precision in high dose gradient regions, using the distance to agreement concept (DTA), showed also satisfactory results. In all investigated cases, the mean DTA was less than 1 mm in build-up and penumbra regions. In regards to calculation efficiency, the event processing speed is six times faster using Geant4-[mt] compared to sequential Geant4, when running the same simulation code for both. The developed VSM for 6 MV/10 MV beams widely used, is a general concept easy to adapt in order to reconstruct comparable beam qualities for various linac configurations, facilitating its integration for MC treatment planning purposes.
DOI: 10.1088/1361-6560/aab7a1
PubMed: 29553478
Affiliations:
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Le document en format XML
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<term>Particle Accelerators (MeSH)</term>
<term>Photons (MeSH)</term>
<term>Programming Languages (MeSH)</term>
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<term>Reproducibility of Results (MeSH)</term>
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<term>Dosimétrie en radiothérapie (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Langages de programmation (MeSH)</term>
<term>Logiciel (MeSH)</term>
<term>Loi normale (MeSH)</term>
<term>Méthode de Monte Carlo (MeSH)</term>
<term>Photons (MeSH)</term>
<term>Planification de radiothérapie assistée par ordinateur (méthodes)</term>
<term>Reproductibilité des résultats (MeSH)</term>
<term>Simulation numérique (MeSH)</term>
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<term>Databases, Factual</term>
<term>Humans</term>
<term>Monte Carlo Method</term>
<term>Normal Distribution</term>
<term>Particle Accelerators</term>
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<term>Programming Languages</term>
<term>Radiotherapy Dosage</term>
<term>Reproducibility of Results</term>
<term>Software</term>
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<term>Méthode de Monte Carlo</term>
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<front><div type="abstract" xml:lang="en">The use of phase space in medical linear accelerator Monte Carlo (MC) simulations significantly improves the execution time and leads to results comparable to those obtained from full calculations. The classical representation of phase space stores directly the information of millions of particles, producing bulky files. This paper presents a virtual source model (VSM) based on a reconstruction algorithm, taking as input a compressed file of roughly 800 kb derived from phase space data freely available in the International Atomic Energy Agency (IAEA) database. This VSM includes two main components; primary and scattered particle sources, with a specific reconstruction method developed for each. Energy spectra and other relevant variables were extracted from IAEA phase space and stored in the input description data file for both sources. The VSM was validated for three photon beams: Elekta Precise 6 MV/10 MV and a Varian TrueBeam 6 MV. Extensive calculations in water and comparisons between dose distributions of the VSM and IAEA phase space were performed to estimate the VSM precision. The Geant4 MC toolkit in multi-threaded mode (Geant4-[mt]) was used for fast dose calculations and optimized memory use. Four field configurations were chosen for dose calculation validation to test field size and symmetry effects, [Formula: see text] [Formula: see text], [Formula: see text] [Formula: see text], and [Formula: see text] [Formula: see text] for squared fields, and [Formula: see text] [Formula: see text] for an asymmetric rectangular field. Good agreement in terms of [Formula: see text] formalism, for 3%/3 mm and 2%/3 mm criteria, for each evaluated radiation field and photon beam was obtained within a computation time of 60 h on a single WorkStation for a 3 mm voxel matrix. Analyzing the VSM's precision in high dose gradient regions, using the distance to agreement concept (DTA), showed also satisfactory results. In all investigated cases, the mean DTA was less than 1 mm in build-up and penumbra regions. In regards to calculation efficiency, the event processing speed is six times faster using Geant4-[mt] compared to sequential Geant4, when running the same simulation code for both. The developed VSM for 6 MV/10 MV beams widely used, is a general concept easy to adapt in order to reconstruct comparable beam qualities for various linac configurations, facilitating its integration for MC treatment planning purposes.</div>
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